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Serie A 2025-26 Fixtures Announced As Napoli Begin Title Defence With Trip To Sassuolo

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The Serie A 2025-26 fixtures have been released with a number of eye-catching MD1 games for supporters to look forward to. 

Reigning champions Napoli face a trip to the Mapei Stadium to play Serie B winners Sassuolo. Last season’s runners-up Inter will take on Torino on home soil.

Milan’s new head coach Max Allegri will square off against newly-promoted Cremonese at the San Siro. Elsewhere, recently-appointed Atalanta boss Ivan Juric will oversee the Dea against Pisa at the Gewiss.

Gian Piero Gasperini’s first match as Roma manager will come against Bologna at the Stadio Olimpico. Meanwhile, Juventus will entertain Parma with Cesc Fabregas’ Como taking on Lazio at the Sinigaglia.

Serie A 2025-26 Fixtures

The release of the Serie A 2025-26 fixtures will see a flurry of seasonal outcomes placed on the best offshore sportsbooks. In particular for the Scudetto winners and top four placements.

Inter are currently the slight favorites to reclaim their crown which was snared by Napoli in 2024-25. Antonio Conte’s side will be heavily backed for consecutive titles.

The likes of Atalanta, Juventus, Milan and Roma are amongst the other likely contenders. Como are also generously priced to finish in the European rankings.

Meanwhile, the Serie A 2025-26 fixtures will see Italy’s elite soccer division start on the weekend of August 23. 2025. The new season will have midweek matches on MD9 and MD19. As well as on January 6, 2026.

As usual, there will be four international breaks. These will occur on September 7, 2025, October 12, 2025, November 16, 2025 and March 29, 2026.

The 2025-26 Serie A campaign will conclude on the weekend of May 24, 2026.

Napoli Begin Scudetto Defence With Trip To Sassuolo

Napoli will be aiming to begin their Scudetto defence with a win against recently-promoted Sassuolo. Antonio Conte’s side has every reason to be brimming with confidence.

The Azzurri have won the last four consecutive Serie A H2H meetings by an aggregate score of 14-1. Of the 22 fixtures the two clubs have contested, the champions have won 13 times and lost on just two occasions.

As for the Neroverdi, they’ll be aiming to reaffirm themselves in Italy’s elite soccer division. Prior to their relegation in 2024, Fabio Grosso’s side spent 10 seasons in the top-flight.

The most fruitful campaign came in 2015-16 whereby Sassuolo finished 6th. That ensured qualification to the Europa League where the Watermelon Peel exited the tournament at the group stages in 2016-17.

The First Milan Derby Of The 2025-26 Season

The first Milan derby of the 2025-26 Serie A season comes on MD12. Inter are the home side and the two giants will go toe-to-toe on the weekend of November 23, 2025.

Incoming head coach Christian Chivu want’s Parma’s teenage sensation Giovanni Leoni to follow him to Inter. He is widely considered to be of Italy’s finest defensive prospects and could earn his first derby minutes in this game.

The return Milan derby will be contested on MD28. That is scheduled to be played on the weekend of March 8, 2026.

When Is The Rome Derby?

Serie A followers in the USA won’t have to wait long for the first Rome derby of the 2025-26 season. Bitter rivals Lazio and Roma will scrap it out at the Stadio Olimpico on MD4 which will be played on the weekend of September 21, 2025.

Interestingly, the reverse fixture will be played on the penultimate weekend of the season which is pencilled in for May 17, 2025. So much could hinge on the outcome of the fiery encounter for new head coaches Gian Piero Gasperini and Maurizio Sarri.

Serie A Winter Break

There will be no Serie A winter break in the 2025-26 campaign. That means the 20 participants in Italy’s elite soccer division will be in action on the weekends of December 21, December 28 and January 3, 2026.

There will be an additional midweek round scheduled for January 6. That means there will only be four interuptions during 2025-26 which is for the quartet of international breaks.

Ben Horlock

Ben has a long standing devotion to Italian soccer and in particular, Serie A. Ben grew up watching legendary presenter James Richardson deliver the latest news and views with the daily papers and breakfast in hand. Not only does Ben follow Italy's top soccer division, he is an avid follower of all the major European leagues. Ben is an expert on all things Serie A and has produced a number of features and news articles for FootItalia as well as UK-based outlets such as HITC, 90min, GiveMeSport and Betfair. In the US, Ben has been published on ESPN and Sports Illustrated. Ben enjoys delivering the latest news but his favorite area is to produce well-researched, long-form features.